Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Naphthol → Propranolol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Naphthol | HCID 7005 | — |
| 반응물 | 1-(Propan-2-yl)azetidin-3-ol | HCID 544677 | — |
| 생성물 | Propranolol | HCID 4946 | — |
반응 단계
1-(isopropyl)-3-azetidinol and α-naphthol were reacted in the same manner as in Example 6 to form 1-(α-naphthoxy)-3-(iso-propylamino)-2-propanol. Then the propanol was dissolved in anhydrous ether and was converted to a hydrochloride by blowing a hydrochloric acid gas into the resulting solution. As a result 1-(α-naphthoxy)-3-(isopropylamino)-2-propanol hydrochloride melting at 162°-164° C was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04018824 |
| 출처 데이터셋 | uspto-grants-1977_04 |
| ORD ID | ord-cc1887e3dcee4e6ab9cac14005c5667c |
| 출처 메모 | uspto-grants-1977_04 |