Methanol → N,N-diallyl-O-methylisourea

HRID 329003노트

반응식

HRID 329003 반응식
[CH2:1]([N:4]([CH2:7][CH:8]=[CH2:9])[C:5]#[N:6])[CH:2]=[CH2:3].[C-]#N.[K+].[CH3:13][OH:14]>O>[CH2:1]([N:4]([CH2:7][CH:8]=[CH2:9])[C:5](=[NH:6])[O:14][CH3:13])[CH:2]=[CH2:3]

참가 물질

5

반응물 3

HCID 887MethanolHCID 9032Potassium CyanideHCID 10849Cyanamide, diallyl

생성물 1

HCID 21440852N,N-diallyl-O-methylisourea수율 67%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The following reactants were combined in a 1-liter, round-bottom flask: 24.4 g (0.2 mole) diallylcyanamide, 13 g (0.2 mole) KCN and 500 ml methanol. The mixture was heated under reflux for 24 hours, then stripped in vacuo. The residue was dissolved in 250 ml H2O, which was subsequently extracted with three 200 ml portions of diethyl ether. The organic phases were combined, washed with 200 ml of H2O and dried with MgSO4. The solvent was evaporated to yield 20.7 g (67% yield) of N,N-diallyl-O-methylisourea.

후처리

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 24 hours
  3. extractionwhich was subsequently extracted with three 200 ml portions of diethyl ether
  4. washwashed with 200 ml of H2O
  5. dry with materialdried with MgSO4
  6. customThe solvent was evaporated

출처 및 근거

ORD 기록
ord-8a9a2033eb344c8d83de7db8b243bb0e
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04018917

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