Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl chloride, 3,4,5-trimethoxy- → 2-Trifluoromethyl-10-[3{4-[2-(3,4,5-trimethoxy-benzoyloxy)-ethoxy]-piperidino}-propyl]-phenothiazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl chloride, 3,4,5-trimethoxy- | HCID 78282 | — |
| 반응물 | Flupimazine | HCID 218089 | — |
| 생성물 | 2-Trifluoromethyl-10-[3{4-[2-(3,4,5-trimethoxy-benzoyloxy)-ethoxy]-piperidino}-propyl]-phenothiazine | HCID 21440927 | 33% |
반응 단계
Using the procedure of Example XXXV, 18.7 g (0.04 mole) of 2-trifluoromethyl-10-[3-(4-β-hydroxyethoxy-piperidino)-propyl]-phenothiazine (prepared in Example XXIII) and 9.2 g (0.04 mole) of 3,4,5-trimethoxy-benzoyl chloride were reacted to obtain 8.5 g (33% yield) of 2-trifluoromethyl-10-[ 3{ 4-[2-(3,4,5-trimethoxy-benzoyloxy)-ethoxy]-piperidino}-propyl]-phenothiazine as a clear amber oil
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04018922 |
| 출처 데이터셋 | uspto-grants-1977_04 |
| ORD ID | ord-590cbc7787f34e64aa1061e0abd7d3b1 |
| 출처 메모 | uspto-grants-1977_04 |