Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → 1-(2-Methyl-6-nitrophenyl)piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 2-Chloro-3-nitrotoluene | HCID 77591 | — |
| 생성물 | 1-(2-Methyl-6-nitrophenyl)piperidine | HCID 12798213 | 35% |
반응 단계
Using a procedure similar to Example 8, step (a), 2-chloro-3-methylnitrobenzene (264 mg, 1.53 mmol) was heated to 110° C. overnight in 3 mL of piperidine to afford 128 mg (35%) of the title compound and an undetermined amount of starting material. 1H-NMR (CDCl3; 400 MHz): δ 7.41-7.34 (m, 2H), 7.02 (t, 1H, J=7.7 Hz), 2.96-2.93 (m, 4H), 2.36 (s, 3H), 1.65 (br s, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07427683B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-be105cc7411f4b82a395347f5ce226f9 |
| 출처 메모 | uspto-grants-2008_09 |