(2-Isothiocyanatoethyl)dimethylamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-(4-methyl-5-oxazolyl)ethyl)aminoethyl]thiourea

HRID 329117노트

반응식

HRID 329117 반응식
[CH3:1][C:2]1[N:3]=[CH:4][O:5][C:6]=1[CH2:7][CH2:8][NH:9][CH2:10][CH2:11][NH2:12].[CH3:13][N:14]([CH3:20])[CH2:15][CH2:16][N:17]=[C:18]=[S:19]>>[CH3:13][N:14]([CH3:20])[CH2:15][CH2:16][NH:17][C:18]([NH:12][CH2:11][CH2:10][NH:9][CH2:8][CH2:7][C:6]1[O:5][CH:4]=[N:3][C:2]=1[CH3:1])=[S:19]

참가 물질

3

반응물 2

HCID 3853726(2-Isothiocyanatoethyl)dimethylamineHCID 20557941N-[2-(4-methyl-5-oxazolyl)ethyl]ethylenediamine

생성물 1

HCID 20557897N-(2-Dimethylaminoethyl)-N'-[2-(2-(4-methyl-5-oxazolyl)ethyl)aminoethyl]thiourea

실험 절차

By the procedure of Example 40(a)(ii), N-[2-(4-methyl-5-oxazolyl)ethyl]ethylenediamine [prepared by reacting ethylenediamine with 5-(2-chloroethyl)-4-methyloxazole] is reacted with 2-dimethylaminoethyl isothiocyanate to give the titel compound.

후처리

  1. customto give the titel compound

출처 및 근거

ORD 기록
ord-9f5ad7e38ba14015ab96231102a63067
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04018931

반응 노트

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