Ethyl 3-oxovalerate → Diethyl 2-Propionylazelate

HRID 329287

반응식

HRID 329287 반응식
[C:1]([CH2:5][C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:4])[CH2:2][CH3:3].[CH2:11]([O:13][C:14]([CH:16](C(=O)C)[CH2:17][C:18]#[C:19][CH2:20][CH2:21]CC(OC)=O)=[O:15])[CH3:12].BrCCCCCCC(OCC)=O>>[C:1]([CH:5]([CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][C:14]([O:13][CH2:11][CH3:12])=[O:15])[C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:4])[CH2:2][CH3:3]

참가 물질

4

반응물 3

HCID 78656Ethyl 3-oxovalerateHCID 122490Ethyl 7-bromoheptanoateHCID 22759276Methyl 8-Ethoxycarbonyl-9-oxo-5-decynoate2회

생성물 1

HCID 22759291Diethyl 2-Propionylazelate

실험 절차

The synthesis of this compound is carried out by the procedure of Example 4, Step A, except that an equivalent quantity of ethyl propionylacetate is substituted for the ethyl acetoacetate of Example 4, Step A, and an equivalent quantity of ethyl 7-bromoheptanoate is substituted for the methyl 7-bromo-5-heptynoate of Example 4, Step A. The product, a viscous oil, is used in the next step directly without distillation.

후처리

  1. customThe synthesis of this compound
  2. distillationThe product, a viscous oil, is used in the next step directly without distillation

출처 및 근거

ORD 기록
ord-1d04c4f7b26c455ab875a2cad5831cf3
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04020177

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