Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(S)-2-Amino-2,3-dimethylbutanamide → 5-Acetoxy-2-(1-carbamoyl-1,2-dimethylpropyl-carbamoyl)-6-methyl-nicotinic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (S)-2-Amino-2,3-dimethylbutanamide | HCID 10154071 | — |
| 반응물 | 5-Acetoxy-6-methyl-pyridine-2,3-dicarboxylic acid anhydride | HCID 13799444 | — |
| 생성물 | 5-Acetoxy-2-(1-carbamoyl-1,2-dimethylpropyl-carbamoyl)-6-methyl-nicotinic acid | HCID 13799445 | — |
반응 단계
6.3 g (28.48 mmol) 5-acetoxy-6-methyl-pyridine-2,3-dicarboxylic acid anhydride and 4.1 g (31.33 mmol) 2-methyl-valinamide are stirred under nitrogen for 2 days at room temperature, and then the precipitated crystalline product is filtered off.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04891428 |
| 출처 데이터셋 | uspto-grants-1990_01 |
| ORD ID | ord-2dd1b797f7c845f08bd0654c2c56b35f |
| 출처 메모 | uspto-grants-1990_01 |