Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Hydroxy-1-naphthaldehyde → 2-(5-carboxy-2-benzoxazolyl)-3H-naphtho[2,1-b]pyran-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Hydroxy-1-naphthaldehyde | HCID 12819 | — |
| 반응물 | 2-Ethoxycarbonylmethyl-5-carboxybenzoxazole | HCID 19871424 | — |
| 촉매 | Acetic Acid | HCID 176 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(5-carboxy-2-benzoxazolyl)-3H-naphtho[2,1-b]pyran-3-one | HCID 19871423 | 56% |
반응 단계
A mixture of 2-hydroxy-1-naphthaldehyde (1.72 g, 0.01 mol), 2-ethoxycarbonylmethyl-5-carboxybenzoxazole (2.49 g, 0.01 mol), ethanol (30 mL), piperidine (10 drops), and acetic acid (5 drops) is heated at reflux for 3 hours. After cooling the reaction mixture is filtered to isolate the yellow fluorescent product which is then washed with ethanol and dried in air to yield 2.0 g (56% of theory) of 2-(5-carboxy-2-benzoxazolyl)-3H-naphtho[2,1-b]pyran-3-one having the structure ##STR19##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04892923 |
| 출처 데이터셋 | uspto-grants-1990_01 |
| ORD ID | ord-f256b0f0768d4dde922bb36ecab302f2 |
| 출처 메모 | uspto-grants-1990_01 |