참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Bromide ion | HCID 259 | — |
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Chloroselenobenzene | HCID 21928 | — |
| 반응물 | Benzenesulfinyl chloride | HCID 4190003 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Perbenzoic acid | HCID 523077 | — |
반응 단계
The diene (2) of step (B) is treated with a halogenating agent such as phenylselenyl chloride or bromide or phenylsulfinyl chloride, preferably phenylselenyl chloride, in an approximately equimolar ratio in an inert solvent at about -80° C., for approximately 20 minutes; illustrative of such inert solvents are methylene chloride, ether and the like. After a standard workup the product residue is dissolved in an ethereal solvent, chilled to about 0° C. and oxidized with an agent such as 30% hydrogen peroxide or a peroxy acid such as peroxybenzoic acid to yield a halohydrin analog (3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04894466 |
|---|
| 출처 데이터셋 | uspto-grants-1990_01 |
|---|
| ORD ID | ord-87cf1d353afc46b09fcef30e59489fe9 |
|---|
| 출처 메모 | uspto-grants-1990_01 |
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