(Triphenylphosphoranylidene)acetaldehyde → 5,5-Bis(4-fluorophenyl)-4-(2-ethyl-2H-tetrazol-5-yl)-2,4-pentadienal

HRID 330653노트

반응식

HRID 330653 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:19]2[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([CH2:17][CH3:18])[N:16]=2)[CH:10]=O)=[CH:4][CH:3]=1.C1(P(=[CH:45][CH:46]=[O:47])(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:19]2[CH:20]=[CH:21][C:22]([F:25])=[CH:23][CH:24]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([CH2:17][CH3:18])[N:16]=2)[CH:10]=[CH:45][CH:46]=[O:47])=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 75051(Triphenylphosphoranylidene)acetaldehydeHCID 147238273,3-Bis(4-Fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenal

생성물 1

HCID 545245085,5-Bis(4-fluorophenyl)-4-(2-ethyl-2H-tetrazol-5-yl)-2,4-pentadienal수율 95%

실험 절차

The procedure of Example 50 was repeated using 3.25 g (9.5 mmoles) of 3,3-bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenal and 3.05 g (10.0 mmoles) of triphenylphosphoranylidene acetaldehyde and there was thereby produced 3.3 g (95%) of the title compound; m.p.=117°-120° C.

출처 및 근거

ORD 기록
ord-1053abf34e0b49a9891767c8ebed5280
출처 데이터셋
uspto-grants-1990_01
특허 번호
US04897490

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