N-[(2-bromophenyl)methyl]cyclopropanamine → (rac.)-(1R,5S)-3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid (2-bromobenzyl)cyclopropylamide formate salt

HRID 33072

반응식

ClC(Cl)(Cl)C([O:6][C:7]([N:9]1[CH:14]2[C:15]([C:36](O)=[O:37])=[C:16]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH2:26][O:27][C:28]4[CH:33]=[C:32]([F:34])[CH:31]=[CH:30][C:29]=4[Cl:35])=[CH:20][CH:19]=3)[CH2:17][CH:10]1[CH2:11][N:12]([C:39](=[O:41])[CH3:40])[CH2:13]2)=[O:8])(C)C.[Br:44][C:45]1[CH:55]=[CH:54][CH:53]=[CH:52][C:46]=1[CH2:47][NH:48][CH:49]1[CH2:51][CH2:50]1>>[CH:7]([OH:8])=[O:6].[Br:44][C:45]1[CH:55]=[CH:54][CH:53]=[CH:52][C:46]=1[CH2:47][N:48]([CH:49]1[CH2:50][CH2:51]1)[C:36]([C:15]1[C@@H:14]2[NH:9][C@H:10]([CH2:17][C:16]=1[C:18]1[CH:19]=[CH:20][C:21]([O:24][CH2:25][CH2:26][O:27][C:28]3[CH:33]=[C:32]([F:34])[CH:31]=[CH:30][C:29]=3[Cl:35])=[CH:22][CH:23]=1)[CH2:11][N:12]([C:39](=[O:41])[CH3:40])[CH2:13]2)=[O:37]