1H-inden-1-one → 5-Hydroxy-1H-inden-1-one

HRID 331256

반응식

HRID 331256 반응식
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.Br.CC(O)=[O:14]>>[OH:14][C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[C:1](=[O:10])[CH:2]=[CH:3]2

참가 물질

3

반응물 2

HCID 118153841H-inden-1-oneHCID 21893785Acetic Acid Mixture with Hydrobromic Acid

생성물 1

HCID 596088915-Hydroxy-1H-inden-1-one

실험 절차

The indenone compound prepared in Step 5 is mixed with HBr/AcOH (1:2), and then the resulting mixture is allowed to reflux for 14 to 16 h with stirring, to obtain the 5-hydroxyindenone of formula 19.

후처리

  1. temperatureto reflux for 14 to 16 h

출처 및 근거

ORD 기록
ord-5a38d199137045348f995cf05f4d2bf6
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08877747B2

연결된 노트

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