2,3-Dihydro-6-hydroxy-3-phenylinden-1-one → 1-(2-Fluorophenyl)-2,3-dihydro-3-oxo-1H-inden-5-yl acetate
반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[C:10](=[O:18])[CH2:9]1.[OH:19][C:20]1C=C2C(C(C3C=CC=CC=3)CC2=O)=C[CH:21]=1>>[C:20]([O:17][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][CH:14]=1)[CH:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])[CH2:9][C:10]2=[O:18])(=[O:19])[CH3:21]참가 물질
3
실험 절차
The procedure of Step 3 of Example 1 was repeated except for using 3-(2-fluorophenyl)-2,3-dihydro-6-hydroxyinden-1-one obtained in Step 2 as a starting material instead of 2,3-dihydro-6-hydroxy-3-phenylinden-1-one to obtain the title compound (85%).
출처 및 근거
- ORD 기록
- ord-6823706e4b13467796c048b6f8d375c8
- 출처 데이터셋
- uspto-grants-2014_11
- 특허 번호
- US08877747B2
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