Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Magnesium chloride hexahydrate → Vildagliptin Magnesium(II)-Chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Magnesium chloride hexahydrate | HCID 24644 | — |
| 반응물 | Vildagliptin | HCID 6918537 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Vildagliptin Magnesium(II)-Chloride | HCID 86675510 | — |
반응 단계
0.34 g (1.65 mmole) of magnesium(II)-chloride hexahydrate is dissolved in 15 cm3 of 2-propanol at 50° C. under intensive stirring, and 1.0 g (3.3 mmole) of vildagliptin base is added to the solution. The solution is stirred at room temperature for 2 hours and is subsequently evaporated. The remaining crystalline product is washed with propanol and dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08877799B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-c451687bab2a46079dfc833dbed04ae3 |
| 출처 메모 | uspto-grants-2014_11 |