Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Amino-1-hexanol → N-(6-Hydroxy-hexyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Amino-1-hexanol | HCID 19960 | — |
| 반응물 | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester | HCID 66599292 | — |
| 생성물 | N-(6-Hydroxy-hexyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide | HCID 68444590 | 20% |
반응 단계
As described for example 220, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (180 mg, 0.55 mmol) was converted, using 6-amino-1-hexanol instead of 3-amino-1-propanol, to the title compound (45 mg, 20%) which was obtained as a white solid. MS: m/e=410.3 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08877783B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-03cb6ca59cff48e0a6b93670936f8cfe |
| 출처 메모 | uspto-grants-2014_11 |