Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-[2-(2-Methoxyethoxy)ethoxy]prop-1-yne
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Propargyl bromide | HCID 7842 | — |
| 반응물 | Diethylene Glycol Monomethyl Ether | HCID 8134 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-[2-(2-Methoxyethoxy)ethoxy]prop-1-yne | HCID 18381683 | — |
반응 단계
To a solution of 2 g 2-(2-Methoxy-ethoxy)-ethanol in 20 ml THF 1.8 g KOt-Bu were added at 0° C. After stirring for 10 min 8.1 ml 3-Bromo-propyne (75% in toluene) were added and the mixture was warmed to RT and stirred for 4 h. Then 10 ml of water were added and the mixture was filtered through a chem elut® cartridge by elution with CHCl3. This solution containing the desired product was subjected to the next reaction step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429581B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-d90fa2892b694c848f6f1ca5bfd7cdec |
| 출처 메모 | uspto-grants-2008_09 |