Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (S)-3-(1,3-Dioxolan-2-yl)propyl 2-amino-3-phenylpropanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| 반응물 | 2-(3-Chloropropyl)-1,3-dioxolane | HCID 552072 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | (S)-3-(1,3-Dioxolan-2-yl)propyl 2-amino-3-phenylpropanoate | HCID 71113124 | — |
반응 단계
The title compound was prepared in two steps. Boc-Phe-OH was reacted with 2-(3-chloropropyl)-1,3-dioxolane according to Example 10 Step 1, and the subsequent product reacted with hydrogen chloride in dioxan according to Example 79 Step 5.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08877774B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-981eb4ca7d664fe68fd01923aa795e02 |
| 출처 메모 | uspto-grants-2014_11 |