Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Nitrophenyl)pyridine → 4-(Pyridin-4-yl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Nitrophenyl)pyridine | HCID 259219 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(Pyridin-4-yl)aniline | HCID 1512654 | 90.5% |
반응 단계
A mixture of 4-(4-nitrophenyl)pyridine (274 mg, 1.37 mmol) and Pd—C(10%, 80 mg) in MeOH (10 mL) was hydrogenated under balloon H2 for 20 h. The mixture was then filtered through celite. The filtrate was concentrated in vacuo to give 4-(pyridin-4-yl)aniline as a solid (211 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08877760B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-b136c50eebdc4587874f3fe657e9b211 |
| 출처 메모 | uspto-grants-2014_11 |