참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 5,5-dimethyl-4-(pyrrolidin-1-yl)furan-2(5H)-one | HCID 25247336 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 4-Hydroxy-5,5-dimethyl-2(5H)-furanone | HCID 54720139 | — |
반응 단계
A suspension of 5,5-dimethyl-4-pyrrolidin-1-ylfuran-2(5H)-one (535 mg) in a mixture of MeOH (2 mL) and 5M HCl (8 mL) was heated at 88° C. for 2 hours. The mixture was cooled to room temp., extracted with CHCl3 (10×15 mL), combined, dried over Na2SO4, and evaporated to dryness to give 4-hydroxy-5,5-dimethyl-5H-furan-2-one as light brown solid. Yield: 359 mg, 95%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08877923B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_11 |
|---|
| ORD ID | ord-6057f08f280d40e299280dbdc5fb3106 |
|---|
| 출처 메모 | uspto-grants-2014_11 |
|---|
