3-(Chloromethyl)-1,2,4-oxadiazole → HCID 57421235, 화합물

HRID 333786노트

반응식

HRID 333786 반응식
Cl[CH2:2][C:3]1[N:7]=[CH:6][O:5][N:4]=1.[Cl:8][C:9]1[CH:10]=[C:11]([OH:30])[CH:12]=[CH:13][C:14]=1[CH:15]([CH3:29])[C:16]([OH:28])([C:21]1[CH:26]=[N:25][C:24]([CH3:27])=[CH:23][N:22]=1)[C:17]([F:20])([F:19])[F:18]>>[Cl:8][C:9]1[CH:10]=[C:11]([O:30][CH2:2][C:3]2[N:7]=[CH:6][O:5][N:4]=2)[CH:12]=[CH:13][C:14]=1[CH:15]([CH3:29])[C:16]([C:21]1[CH:26]=[N:25][C:24]([CH3:27])=[CH:23][N:22]=1)([OH:28])[C:17]([F:18])([F:20])[F:19]

참가 물질

3

반응물 2

HCID 27357653-(Chloromethyl)-1,2,4-oxadiazoleHCID 574212313-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol

생성물 1

HCID 57421235HCID 57421235, 화합물

실험 절차

The title compound was prepared in analogy to Example 74 from 3-(chloromethyl)-1,2,4-oxadiazole and 3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol (Example 72). MS (m/e)=429.3 (MH+).

출처 및 근거

ORD 기록
ord-73abb59925c8418bb6be8f0602c1f1ac
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883786B2

반응 노트

불러오는 중…