Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → Ethyl (2-methoxy-6-nitrophenyl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Diphosgene | HCID 10426 | — |
| 반응물 | 6-Nitro-o-anisidine | HCID 85491 | — |
| 생성물 | Ethyl (2-methoxy-6-nitrophenyl)carbamate | HCID 86603972 | — |
반응 단계
17.1 mL (0.141 mol) trichloromethylchloroformate are added dropwise at reflux temperature to a solution of 23.8 g (0.142 mol) 2-methoxy-6-nitro-phenylamine in 300 mL THF and then the mixture is stirred for 4 hours at this temperature. The solvent is distilled off and the residue is stirred with isopropanol, during which time a yellow solid is precipitated. Yield: 25.0 g (73%); mass spectroscopy: [M+H]+=241.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429583B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-5731544a9aa245a3966584cf36fb4237 |
| 출처 메모 | uspto-grants-2008_09 |