(4-Fluoro-3-methylphenyl)boronic acid → 1-(4-Fluoro-3-methyl-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid

HRID 334014

반응식

HRID 334014 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][C:3]=1[CH3:11].[NH:12]1[CH:16]=[N:15][C:14]([C:17]([O:19]C)=[O:18])=[N:13]1.ClC1C=C(N2C=NC(C(O)=O)=N2)C=CC=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:12]2[CH:16]=[N:15][C:14]([C:17]([OH:19])=[O:18])=[N:13]2)=[CH:4][C:3]=1[CH3:11]

참가 물질

4

실험 절차

This intermediate was prepared from 4-fluoro-3-methylphenylboronic acid and methyl 1,2,4-triazole-3-carboxylate in two steps according to the preparation of 1-(3-chloro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid.

출처 및 근거

ORD 기록
ord-e9e542b5665247388e662b49da6cfc57
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883789B2

연결된 노트

불러오는 중…