1-Bromo-4-fluoro-2-iodobenzene → 5-Fluoro-methyl-benzofuran-3-carboxylic acid

HRID 334068

반응식

HRID 334068 반응식
Br[C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1I.BrC1C=CC2[O:18][C:17]([CH3:19])=[C:16]([C:20]([OH:22])=[O:21])C=2C=1>>[F:8][C:5]1[CH:6]=[CH:7][C:2]2[O:18][C:17]([CH3:19])=[C:16]([C:20]([OH:22])=[O:21])[C:3]=2[CH:4]=1

참가 물질

3

반응물 2

HCID 27733701-Bromo-4-fluoro-2-iodobenzeneHCID 866882905-Bromo-methyl-benzofuran-3-carboxylic acid

생성물 1

HCID 833973655-Fluoro-methyl-benzofuran-3-carboxylic acid

실험 절차

This intermediate was prepared from 1-bromo-4-fluoro-2-iodo-benzene in two steps according to the preparation of 5-bromo-methyl-benzofuran-3-carboxylic acid (from 1,4-dibromo-2-iodo-benzene).

출처 및 근거

ORD 기록
ord-05bca94a70774e0ea703b0222e71d526
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883789B2

연결된 노트

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