Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2,4-Xylyl)piperazine → 1-(Biphenyl-2-ylmethyl)-4-(2,4-dimethylphenyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2,4-Xylyl)piperazine | HCID 70544 | — |
| 반응물 | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 반응물 | 1-(Biphenyl-2-ylmethyl)-4-phenylpiperazine | HCID 71602523 | — |
| 생성물 | 1-(Biphenyl-2-ylmethyl)-4-(2,4-dimethylphenyl)piperazine | HCID 71602642 | — |
반응 단계
201.6 mg of the target compound (0.57 mmol, 69.0%) was obtained using 1-(2,4-dimethylphenyl)piperazine (312 mg, 1.64 mmol), biphenyl-2-carbaldehyde (150 mg, 0.82 mmol) and NaBH(OAc)3 (529 mg, 2.46 mmol) according to the synthesis method of Compound 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08883796B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-32ccbbe1bb704f5eb502340b1cb11392 |
| 출처 메모 | uspto-grants-2014_11 |