Methyl 5-amino-6-methylnicotinate → Methyl 5-(7-bromoimidazo[1,2-a]pyridine-3-carboxamido)-6-methylnicotinate

HRID 335313

반응식

HRID 335313 반응식
[Br:1][C:2]1[CH:7]=[CH:6][N:5]2[C:8]([C:11](NC3C=C(C=CC=3F)C(O)=O)=[O:12])=[CH:9][N:10]=[C:4]2[CH:3]=1.[NH2:24][C:25]1[C:26]([CH3:35])=[N:27][CH:28]=[C:29]([CH:34]=1)[C:30]([O:32][CH3:33])=[O:31]>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]2[C:8]([C:11]([NH:24][C:25]3[C:26]([CH3:35])=[N:27][CH:28]=[C:29]([CH:34]=3)[C:30]([O:32][CH3:33])=[O:31])=[O:12])=[CH:9][N:10]=[C:4]2[CH:3]=1

참가 물질

3

반응물 2

HCID 58662456Methyl 5-amino-6-methylnicotinateHCID 712834433-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluorobenzoic acid2회

생성물 1

HCID 71282997Methyl 5-(7-bromoimidazo[1,2-a]pyridine-3-carboxamido)-6-methylnicotinate

실험 절차

The title compound was prepared from 7-bromoimidazo[1,2-a]pyridine-3-carboxylic acid (Intermediate 1A, step 3) and methyl 5-amino-6-methylnicotinate (step 2) analogously to Intermediate 1A;

출처 및 근거

ORD 기록
ord-f05258628aa2480dac88ccb4a6c0116d
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883819B2

연결된 노트

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