2-Amino-8-quinolinol → HCID 178507286, 화합물

HRID 33551

반응식

HRID 33551 반응식
Cl[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][C:9]([C:11]([F:14])([F:13])[F:12])=[CH:10][C:4]=2[N:3]=1.[NH2:15][C:16]1[CH:25]=[CH:24][C:23]2[C:18](=[C:19]([OH:26])[CH:20]=[CH:21][CH:22]=2)[N:17]=1>>[F:12][C:11]([F:14])([F:13])[C:9]1[CH:8]=[CH:7][C:5]2[NH:6][C:2]([O:26][C:19]3[CH:20]=[CH:21][CH:22]=[C:23]4[C:18]=3[N:17]=[C:16]([NH2:15])[CH:25]=[CH:24]4)=[N:3][C:4]=2[CH:10]=1

참가 물질

3

반응물 2

HCID 46537882-Amino-8-quinolinolHCID 178506089HCID 178506089, 화합물

생성물 1

HCID 178507286HCID 178507286, 화합물

실험 절차

The reaction of 2-chloro-5-(trifluoromethyl)-1H-benzo[d]imidazole (66 mg, 0.3 mol, prepared according to the procedure described in WO 2004/035549 A1) with 2-amino-8-hydroxyquinoline (48 mg, 0.3 mmol, Fluka) under the condition of Example 1 afforded the title compound as an amorphous solid. MS (ESI, pos. ion) m/z: 345 (M+1).

후처리

  1. customprepared

출처 및 근거

ORD 기록
ord-473cec72afb648489e70008e8513c2e0
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429608B2

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