HCID 58564023, 화합물 → Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide

HRID 336203노트

반응식

HRID 336203 반응식
[O:1]=[S:2]1(=[O:14])[CH2:7][CH2:6][C:5](C(O)=O)([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1>CN(C=O)C>[O:1]=[S:2]1(=[O:14])[CH2:7][CH2:6][CH:5]([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1

참가 물질

3

반응물 1

HCID 58564023HCID 58564023, 화합물

생성물 1

HCID 1491755Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

In a microwave vial is added 1,1-Dioxo-tetrahydro-1λ6-thiopyran-4,4-dicarboxylic acid (112 mg; 0.504 mmol), 2% cross-linked poly-4-vinylpyridine (225 mg) and DMF (2.1 mL). The vial is sealed and placed into microwave oven for 10 minutes at 95° C. After cooling, the mixture is filtered through filter paper and washed the paper with diethyl ether. The filtrate is concentrated in vacuo to afford the title compound.

후처리

  1. customThe vial is sealed
  2. temperatureAfter cooling
  3. filtrationthe mixture is filtered
  4. filtrationthrough filter paper
  5. washwashed the paper with diethyl ether
  6. concentrationThe filtrate is concentrated in vacuo

출처 및 근거

ORD 기록
ord-7eb3610a0c0e4937a651665e8d86db4a
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08889670B2

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