4-Fluorobenzohydrazide → 3,5-bis-(4-Fluoro-phenyl)-1H-(1,2,4)triazole

HRID 336371

반응식

HRID 336371 반응식
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[NH:7])=[CH:4][CH:3]=1.[F:11][C:12]1[CH:21]=[CH:20][C:15]([C:16]([NH:18]N)=O)=[CH:14][CH:13]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]2[N:8]=[C:16]([C:15]3[CH:20]=[CH:21][C:12]([F:11])=[CH:13][CH:14]=3)[NH:18][N:7]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 99724-FluorobenzohydrazideHCID 42952384-Fluorobenzamidine

생성물 1

HCID 866865153,5-bis-(4-Fluoro-phenyl)-1H-(1,2,4)triazole수율 71.2%

실험 절차

4 g 4-fluoro-benzamidine was added to 4.5 g 4-fluoro-benzoic acid hydrazide and this mixture was melted. This mixture was crystallized with ethyl acetate to give 5.3 g of the desired compound. Rt: 1.55 min (method A), (M+H)+: 258

후처리

  1. customThis mixture was crystallized with ethyl acetate

출처 및 근거

ORD 기록
ord-a205307911b24c539cfb490c3a282420
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08889677B2

연결된 노트

불러오는 중…