Benzaldehyde → 1-(3-(1h-Imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione

HRID 336818

반응식

HRID 336818 반응식
[N:1]1([CH2:6][CH2:7][CH2:8][NH2:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[CH:10](=[O:17])C1C=CC=CC=1.[CH2:18]([N+]#[C-])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[O:27]([C:29]#[N:30])[K]>>[N:1]1([CH2:6][CH2:7][CH2:8][N:9]2[CH:18]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:29](=[O:27])[NH:30][C:10]2=[O:17])[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

5

반응물 4

HCID 240BenzaldehydeHCID 787361H-Imidazole-1-propanamineHCID 82558Benzyl isocyanideHCID 178418250HCID 178418250, 화합물

생성물 1

HCID 461812681-(3-(1h-Imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione

실험 절차

The compound was synthesized starting from 3-(1H-imidazol-1-yl)propylamine 1.0 g (7.98 mmol), benzaldehyde 0.807 ml (7.98 mmol), benzylisonitrile 0.972 ml (7.98 mmol), pyidiniumchloride 0.920 and KOCN 0.648 g (7.98 mmol) as described in method 1.

후처리

  1. customThe compound was synthesized

출처 및 근거

ORD 기록
ord-6a6efb9c2d1e4baa83497ba8bbbb9625
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08889709B2

연결된 노트

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