Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2Z)-3-(2-cyanophenyl)prop-2-enoic acid → 3-(2-Cyanophenyl)propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2Z)-3-(2-cyanophenyl)prop-2-enoic acid | HCID 1899166 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(2-Cyanophenyl)propanoic acid | HCID 12398850 | 90.7% |
반응 단계
A slurry of (Z)-3-(2-cyanophenyl)acrylic acid (Example 323a, 4.75 g) in ethanol (50 mL) was added to 5% Palladium (0.292 g) in ethanol (50 mL) and hydrogenated under 2.0 bar hydrogen pressure for 2 h. The reaction mixture was filtered and the filtrate evaporated to dryness to afford the sub title compound as a solid (4.36 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889692B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-2a6afa11b5114cea90721941c661a8bc |
| 출처 메모 | uspto-grants-2014_11 |