Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyrazole → 2,2-dimethyl-1-(1-methyl-1H-pyrazol-5-yl)Cyclopentanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyrazole | HCID 1048 | — |
| 반응물 | 2,2-Dimethylcyclopentanone | HCID 138286 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2,2-dimethyl-1-(1-methyl-1H-pyrazol-5-yl)Cyclopentanol | HCID 79863038 | 7.3% |
반응 단계
The reaction and aftertreatment were conducted in the same manner as in Example 8a by using pyrazole (3.70 g, 45.1 mmol), n-butyl lithium (2.69 M solution in hexane; 17 mL, 45.7 mmol), 2,2-dimethylcyclopentanone (5.00 g, 44.6 mmol) and THF (100 mL), to yield the title compound (630 mg, 7.3%) as a colorless solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889741B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-fd8cd709a1254c549eb6dcc43a7ba25a |
| 출처 메모 | uspto-grants-2014_11 |