돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 337877생성일: 2026년 10월 25일

Pyrazole → 2,2-dimethyl-1-(1-methyl-1H-pyrazol-5-yl)Cyclopentanol

https://huagongshe.com/reaction/337877

반응식

참여 물질

역할이름HCID투입량
반응물PyrazoleHCID 1048—
반응물2,2-DimethylcyclopentanoneHCID 138286—
반응물ButyllithiumHCID 178418339—
용매TetrahydrofuranHCID 8028—
생성물2,2-dimethyl-1-(1-methyl-1H-pyrazol-5-yl)CyclopentanolHCID 798630387.3%

반응 단계

The reaction and aftertreatment were conducted in the same manner as in Example 8a by using pyrazole (3.70 g, 45.1 mmol), n-butyl lithium (2.69 M solution in hexane; 17 mL, 45.7 mmol), 2,2-dimethylcyclopentanone (5.00 g, 44.6 mmol) and THF (100 mL), to yield the title compound (630 mg, 7.3%) as a colorless solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08889741B2
출처 데이터셋uspto-grants-2014_11
ORD IDord-fd8cd709a1254c549eb6dcc43a7ba25a
출처 메모uspto-grants-2014_11