Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → HCID 89963326, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,4-Difluoropyrimidine | HCID 137716 | — |
| 반응물 | HCID 89963518 | HCID 89963518 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 89963326 | HCID 89963326 | 70.2% |
반응 단계
The reaction and aftertreatment were conducted in the same manner as in Example 111d by using the 2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclopentyl]oxy}benzenesulfonamide (0.16 g, 0.47 mmol) prepared in Example 114c, 2,4-difluoropyrimidine (0.16 g, 1.41 mmol), potassium carbonate (0.26 g, 1.88 mmol) and DMF (4.7 mL), to yield the title compound (143.6 mg, 70%) as a colorless amorphous solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889741B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-d65347fd72d34332b2542c5cfc22c51f |
| 출처 메모 | uspto-grants-2014_11 |