Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1-(4-Bromophenyl)cyclobutyl)methanol → 4,6-difluoro-5-(4-(1-(hydroxymethyl)cyclobutyl)phenyl)-1H-indole-3-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1-(4-Bromophenyl)cyclobutyl)methanol | HCID 58538689 | — |
| 반응물 | 5-Bromo-4,6-difluoro-1H-indole-3-carbaldehyde | HCID 86698578 | — |
| 생성물 | 4,6-difluoro-5-(4-(1-(hydroxymethyl)cyclobutyl)phenyl)-1H-indole-3-carbaldehyde | HCID 86698845 | — |
반응 단계
[1-(4-bromophenyl)cyclobutyl]methanol, prepared as described in Example 72 (steps 1 and 2), is treated with 5-bromo-4,6-difluoro-1H-indole-3-carbaldehyde, prepared as described in Example 6 (steps 1-4), in a manner similar as described in Example 6 step 5 to provide the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889730B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-11765295e5174708a5b780ec3251fd15 |
| 출처 메모 | uspto-grants-2014_11 |