2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-one → 1-{2-Fluoro-4-(quinolin-2-ylmethoxy)-phenyl}-2-pyridin-4-yl-ethanone

HRID 33854

반응식

HRID 33854 반응식
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:12][CH:11]=2)=[O:9])=[CH:3][CH:2]=1.[F:28]C1C=C(OCC2C=CC3C(=CC=CC=3)N=2)C=CC=1C(N(OC)C)=O>>[F:28][C:11]1[CH:12]=[C:13]([O:16][CH2:17][C:18]2[CH:27]=[CH:26][C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[N:19]=2)[CH:14]=[CH:15][C:10]=1[C:8](=[O:9])[CH2:7][C:4]1[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=1

참가 물질

3

반응물 2

HCID 336797272-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-oneHCID 862492922-Fluoro-n-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide

생성물 1

HCID 685783611-{2-Fluoro-4-(quinolin-2-ylmethoxy)-phenyl}-2-pyridin-4-yl-ethanone

실험 절차

Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting 2-Fluoro-n-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide provided the title compound. MS: (M+H m/z=373.0).

출처 및 근거

ORD 기록
ord-f6434468728c4621afd9a6920353e9a1
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429665B2

연결된 노트

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