Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 4-(2-Quinolin-2-yl-ethyl)-benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-(2-Quinolin-2-yl-ethyl)-benzoic acid methyl ester | HCID 68575869 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-(2-Quinolin-2-yl-ethyl)-benzoic acid | HCID 68576307 | 86% |
반응 단계
To a solution of 4-(2-Quinolin-2-yl-ethyl)-benzoic acid methyl ester (680 mg) in THF (11 ml)/methanol (3 ml) was added 1N sodium hydroxide solution (4.67 ml). The reaction mixture stirred for 4 h. and the pH adjusted to 3. The white solid was filtered to provide the title compound (550 mg, 86%). MS: (M+H m/z=278.1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429665B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-0cc8621753b5413c8299f25a9bc3a651 |
| 출처 메모 | uspto-grants-2008_09 |