4-(Trifluoromethyl)aniline → 4-Bromo-N-(4-(trifluoromethyl)phenyl)picolinamide

HRID 338727

반응식

HRID 338727 반응식
[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([OH:10])=O)[CH:3]=1.[F:11][C:12]([F:21])([F:20])[C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([NH:17][C:16]2[CH:18]=[CH:19][C:13]([C:12]([F:11])([F:20])[F:21])=[CH:14][CH:15]=2)=[O:10])[CH:3]=1

참가 물질

3

반응물 2

HCID 99644-(Trifluoromethyl)anilineHCID 7351504-Bromopyridine-2-carboxylic acid

생성물 1

HCID 866958514-Bromo-N-(4-(trifluoromethyl)phenyl)picolinamide

실험 절차

In a manner similar to that describe in Preparation 34, 4-bromo-pyridine-2-carboxylic acid and 4-trifluoromethylaniline were converted to the title compound.

출처 및 근거

ORD 기록
ord-604242517c504b18bb8a23924dfac4ea
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08889870B2

연결된 노트

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