참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 3-Bromo-4-hydroxybenzaldehyde | HCID 76308 | — |
| 반응물 | 2-Amino-4-(trifluoromethyl)benzenethiol | HCID 88042 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 60194686 | HCID 60194686 | — |
반응 단계
In a DMF (3 mL) solvent, a solution including 2-amino-4-trifluoromethylbenzenethiol (100 mg, 0.44 mmol) and 3-bromo-4-hydroxybenzaldehyde (88.4 mg, 0.44 mmol) was heated at a temperature of 100° C. for 2.5 hours. After DMF was evaporated, the residual was distributed between methylene chloride and water, and an organic layer was evaporated. The produced solid was filtered, and washed with ethyl acetate to obain a solid Compound 119.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08889881B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_11 |
|---|
| ORD ID | ord-072af3e54f1840808a101805588a7fcc |
|---|
| 출처 메모 | uspto-grants-2014_11 |
|---|
