Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydrazinopyridine → 2-[4-(2-Pyridin-4-yl-2H-[1,2,4]triazol-3-yl)-phenoxymethyl]-quinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydrazinopyridine | HCID 416631 | — |
| 반응물 | 2-[4-(5-Pyridin-4-yl-[1,2,4]triazol-1-yl)-phenoxymethyl]-quinoline | HCID 11660880 | — |
| 반응물 | 4-(Quinolin-2-ylmethoxy)benzamide | HCID 44088007 | — |
| 생성물 | 2-[4-(2-Pyridin-4-yl-2H-[1,2,4]triazol-3-yl)-phenoxymethyl]-quinoline | HCID 11646578 | — |
반응 단계
Following the procedure for the preparation of 2-[4-(5-Pyridin-4-yl-[1,2,4]triazol-1-yl)-phenoxymethyl]-quinoline but substituting 4-(Quinolin-2-ylmethoxy)-benzamide and Pyridin-4-yl-hydrazine provided the title compound. 1H NMR (400 MHz, CDCl3) δ 8.65 (d, J=6.2 Hz, 2 H), 8.21 (d, J=8.3 Hz, 1 H), 8.08 (s, 1H), 8.07 (d, J=7.9 Hz, 1H), 7.84 (d, J=8.3 Hz, 1H), 7.73 (m, 1 H), 7.65 (d, J=8.7 Hz, 1 H), 7.55 (m, 1 H), 7.43 (d, J=9.1 Hz, 2H), 7.32 (d, J=6.2 Hz, 2 H), 7.05 (d, J=8.7Hz, 2H), 5.40 (s, 2H); MS: (M+H m/z=380.2).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429665B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-163c620ed7a54db1b77b8c6a9792a924 |
| 출처 메모 | uspto-grants-2008_09 |