Benzyl Bromide → Benzyl 4-benzyloxy-2-fluorobenzoate

HRID 33895

반응식

HRID 33895 반응식
[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15]C=CC=3)N=2)=[CH:6][CH:5]=1.C(Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.[F:31]C1C=C(O)C=CC=1C(O)=O>>[CH2:1]([O:2][C:3](=[O:22])[C:4]1[CH:5]=[CH:6][C:7]([O:10][CH2:11][C:12]2[CH:21]=[CH:20][CH:19]=[CH:14][CH:15]=2)=[CH:8][C:9]=1[F:31])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

참가 물질

4

반응물 3

HCID 7498Benzyl BromideHCID 27833982-Fluoro-4-hydroxybenzoic AcidHCID 19934817Methyl 4-(2-quinolinylmethoxy)benzoate

생성물 1

HCID 57916590Benzyl 4-benzyloxy-2-fluorobenzoate

실험 절차

Following the procedure for the preparation of 4-(Quinolin-2-ylmethoxy)-benzoic acid methyl ester but substituting two equivalents of benzyl bromide and 2-Fluoro4-hydroxy-benzoic acid provided the title compound. MS: (M+H m/z=337.2).

출처 및 근거

ORD 기록
ord-1a5c99359f244509a88127ccbce3db88
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429665B2

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