Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pivaloyl chloride → 2,2-Dimethyl-propionic acid 10-bromodecyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pivaloyl chloride | HCID 62493 | — |
| 반응물 | 1-Decanol, 10-bromo- | HCID 104507 | — |
| 촉매 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 2,2-Dimethyl-propionic acid 10-bromodecyl ester | HCID 57333781 | 85% |
반응 단계
2,2-dimethyl-propionic acid 10-bromodecyl ester was prepared in 85% yield by treatment of 10-bromodecan-1-ol with trimethylacetyl chloride in the presence of pyridine and 4-dimethylaminopyridine at room temperature in dithlcromethane. After 18 hrs, the reaction was quenched by the addition of dilute hydrochloric acid worked up and filtered through silica to provide 2,2-dimethyl-propionic acid 10-bromodecyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889894B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-628f7a29ee99450882d8c5c0698fc2e3 |
| 출처 메모 | uspto-grants-2014_11 |