D-Leucine, methyl ester → (R)-methyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)pentanoate

HRID 339336

반응식

HRID 339336 반응식
[CH3:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[C:11]([OH:13])=O.[CH3:14][O:15][C:16](=[O:23])[C@@H:17]([CH2:19][CH:20]([CH3:22])[CH3:21])[NH2:18]>>[CH3:21][CH:20]([CH3:22])[CH2:19][C@@H:17]([NH:18][C:11]([C:3]1[O:4][C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:2]=1[CH3:1])=[O:13])[C:16]([O:15][CH3:14])=[O:23]

참가 물질

3

반응물 2

HCID 89967D-Leucine, methyl esterHCID 6005913-Methyl-1-benzofuran-2-carboxylic acid

생성물 1

HCID 52461312(R)-methyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)pentanoate

실험 절차

Prepared in a similar manner to example 4 using 3-methylbenzofuran-2-carboxylic acid and D-leucine methyl ester. MS (M+H, 304).

출처 및 근거

ORD 기록
ord-7df557c35bca468ea1350e8e7adc2496
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895050B2

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