(+)-L-Leucine methyl ester → (R)-methyl 4-methyl-2-(4-(methylthio)benzamido)pentanoate

반응식

[CH3:1][S:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=1.[CH3:12][O:13][C:14](=[O:21])[C@H:15]([CH2:17][CH:18]([CH3:20])[CH3:19])[NH2:16]>>[CH3:19][CH:18]([CH3:20])[CH2:17][C@@H:15]([NH:16][C:7](=[O:9])[C:6]1[CH:5]=[CH:4][C:3]([S:2][CH3:1])=[CH:11][CH:10]=1)[C:14]([O:13][CH3:12])=[O:21]

참가 물질

반응물 2

HCID 65105(+)-L-Leucine methyl ester

HCID 832304-(Methylthio)benzoic acid

생성물 1

HCID 37992989(R)-methyl 4-methyl-2-(4-(methylthio)benzamido)pentanoate

실험 절차

Prepared in a similar manner to example 4 using 4-(methylthio)benzoic acid and D Leucine methyl ester. MS (M+H, 296).

출처 및 근거

ORD 기록: ord-25e93c6a36774ea08835a4102e13b1db
출처 데이터셋: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08895050B2

반응 노트

불러오는 중…