D-Leucine, methyl ester → (R)-methyl 2-(3-fluoro-4-methoxybenzamido)-4-methylpentanoate

HRID 339351

반응식

HRID 339351 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.[CH3:13][O:14][C:15](=[O:22])[C@@H:16]([CH2:18][CH:19]([CH3:21])[CH3:20])[NH2:17]>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([NH:17][C@H:16]([CH2:18][CH:19]([CH3:21])[CH3:20])[C:15]([O:14][CH3:13])=[O:22])=[O:7]

참가 물질

3

반응물 2

HCID 89967D-Leucine, methyl esterHCID 27334013-Fluoro-4-methoxybenzoic acid

생성물 1

HCID 32044601(R)-methyl 2-(3-fluoro-4-methoxybenzamido)-4-methylpentanoate

실험 절차

Prepared in a similar manner to example 4 using 3-fluoro-4-methoxybenzoic acid and D-leucine methyl ester. MS (M+H, 298).

출처 및 근거

ORD 기록
ord-828a6c980fb84500a3385c0d9b1942cb
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895050B2

연결된 노트

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