3-Chloro-p-anisic acid → (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate

HRID 339353

반응식

HRID 339353 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.Cl.[CH3:14][O:15][C:16](=[O:23])[C@@H:17]([CH2:19][CH:20]([CH3:22])[CH3:21])[NH2:18]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([NH:18][C@H:17]([CH2:19][CH:20]([CH3:22])[CH3:21])[C:16]([O:15][CH3:14])=[O:23])=[O:7]

참가 물질

3

반응물 2

HCID 1699823-Chloro-p-anisic acidHCID 11600782D-Leucine Methyl Ester Hydrochloride

생성물 1

HCID 57527984(R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate

실험 절차

Prepared in a similar manner to example 4 using 3-chloro-4-methoxy benzoic acid and D-leucine methyl ester hydrochloride. MS (M+H, 314.10).

출처 및 근거

ORD 기록
ord-eff9efd56447445a92417cfd673123f0
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895050B2

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