Stannous chloride dihydrate → 4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline

HRID 339500

반응식

HRID 339500 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[S:11][C:12]3[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:13]=3[N:14]=2)=[CH:6][CH:5]=1)([O-])=O.O.O.[Sn](Cl)Cl>CCO>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[S:11][C:12]3[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:13]=3[N:14]=2)=[CH:8][CH:9]=1

참가 물질

4

반응물 2

HCID 61436Stannous chloride dihydrateHCID 106608526-Methoxy-2-(4-nitrophenyl) benzothiazole

생성물 1

HCID 3918704-(6-Methoxy-1,3-benzothiazol-2-yl)aniline수율 93.6%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Prepared as described in the Nitro Reduction section using 2-(4-nitrophenyl)-6-methoxybenzothiazole (5.0 g, 17.5 mmol) and tin (II) dichloride dihydrate (31.5 g, 0.14 mol) in EtOH (150 ml) to give the title compound (4.2 g, 93%) as a colourless solid after work-up and recrystallisation from EtOH.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-15f369d2d1e442018b37cb1474605b38
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895313B2

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