2-Methoxy-4-nitrobenzaldehyde → 2-Hydroxy-4-nitrobenzaldehyde

HRID 339593

반응식

HRID 339593 반응식
C[O:2][C:3]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:4]=1[CH:5]=[O:6]>C(Cl)Cl.B(Br)(Br)Br>[OH:2][C:3]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:4]=1[CH:5]=[O:6]

참가 물질

4

반응물 1

HCID 27595992-Methoxy-4-nitrobenzaldehyde

생성물 1

HCID 755702-Hydroxy-4-nitrobenzaldehyde수율 78%

시약·촉매·용매 2

HCID 6344Dichloromethane용매2회HCID 25134Boron tribromide용매

실험 절차

Prepared as described in the Demethylation section above using 2-methoxy-4-nitrobenzaldehyde (1.0 g, 5.52 mmol) in dry DCM (25 ml) and BBr3 in DCM (1.0 M, 16 ml, 16 mmol) to give the title compound (0.70 g, 78%) as tan plates after recrystallisation from EtOH.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-8c1625e8d0ab443193ea50f7d0b0a35b
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895313B2

연결된 노트

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