Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Hydrazinyl-4-(2-methoxyethoxy)pyridine → N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-(2-methoxyethoxy)pyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Hydrazinyl-4-(2-methoxyethoxy)pyridine | HCID 55279043 | — |
| 반응물 | 8-(Tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde | HCID 58567082 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-(2-methoxyethoxy)pyridin-2-amine | HCID 173055441 | 56% |
반응 단계
2-Hydrazinyl-4-(2-methoxyethoxy)pyridine (0.076 g, 0.415 mmol) and 8-(tert-butyldimethylsilyloxy) quinoline-2-carbaldehyde (0.119 g, 0.415 mmol) were heated to reflux in EtOH (2 mL) for 16 hours. After cooling to ambient temperature the reaction mixture was filtered and washed with EtOH to provide 105 mg (56%) of desired product as an orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08895550B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-54203cd3635c4e7f9b56a7890bb40afa |
| 출처 메모 | uspto-grants-2014_11 |