Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyltriphenylphosphonium bromide → 8-Phenethylbenzo[f][1,7]naphthyridin-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyltriphenylphosphonium bromide | HCID 2734970 | — |
| 반응물 | 5-Aminobenzo[f][1,7]naphthyridine-8-carbaldehyde | HCID 86652355 | — |
| 생성물 | 8-Phenethylbenzo[f][1,7]naphthyridin-5-amine | HCID 58213779 | — |
반응 단계
8-Phenethylbenzo[f][1,7]naphthyridin-5-amine was prepared from 5-aminobenzo[f][1,7]naphthyridine-8-carbaldehyde (from Example 87) with benzyltriphenylphosphonium bromide following the procedures described for Example 91 (wittig reaction) and Example 92 (reduction). 1H NMR (acetone-d6): δ 8.99 (dd, 1H), 8.88 (dd, 1H), 8.35 (d, 1H), 7.83 (dd, 1H), 7.49 (d, 1H), 7.29-7.15 (dd, 6H), 6.70 (br s, 2H), 3.10-3.00 (m, 4H). LRMS [M+H]=300.1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08895577B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-34cec331caf449b1985d8e1a8a81128d |
| 출처 메모 | uspto-grants-2014_11 |