Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → propargyl N-methoxy-2,4-dichlorobenzimidate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Propargyl bromide | HCID 7842 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,4-dichloro-N-methoxybenzamide | HCID 18935035 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | propargyl N-methoxy-2,4-dichlorobenzimidate | HCID 53654798 | 29.8% |
반응 단계
1.0 g of N-methoxy-2,4-dichlorobenzamide, 0.75 g of potassium carbonate and 0.65 g of propargyl bromide were added to 10 ml of N,N-dimethylformamide, and the mixture was stirred for 3 hours. After completion of the reaction, water was added to the reaction solution, and the mixture was extracted with ethyl acetate. The extract was dried, concentrated and purified by silica gel column chromatography to obtain 0.35 g of propargyl N-methoxy-2,4-dichlorobenzimidate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05733935 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-bc47ddbc82764811b755545cf676a4fc |
| 출처 메모 | uspto-grants-1998_03 |