(Phenylmethyl)hydrazine → 2-benzyl-5-(2-naphthyl)-2H-pyrazol-3-ylamine

HRID 34056노트

반응식

HRID 34056 반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11](=O)[CH2:12][C:13]#[N:14].[CH2:16]([NH:23][NH2:24])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([N:23]1[C:13]([NH2:14])=[CH:12][C:11]([C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)=[N:24]1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

참가 물질

3

반응물 2

HCID 11157(Phenylmethyl)hydrazineHCID 222856beta-Oxo-2-naphthalenepropanenitrile

생성물 1

HCID 230701332-benzyl-5-(2-naphthyl)-2H-pyrazol-3-ylamine

실험 절차

900 mg of 2-benzyl-5-(2-naphthyl)-2H-pyrazol-3-ylamine obtained from 3-(naphthalen-2-yl)-3-oxopropionitrile and benzyl hydrazine in the similar method as described in Production example 30 was subjected to the similar reaction as described in Production example 31, to afford 770 mg of the title compound as a pale yellow powder.

출처 및 근거

ORD 기록
ord-7483e6c6f8f1442d9708eba5f6da490e
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429609B2

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